王辰 |
呼吸系统疾病基础与临床研究;群医学与公共卫生研究
王辰,呼吸病学与危重症医学专家。中国工程院院士,美国国家医学科学院外籍院士,欧洲科学院外籍院士,欧洲科学与艺术学院院士,中国医学科学院学部委员。中国工程院副院长,中国医学科学院院长,北京协和医学院校长。国家呼吸医学中心主任。世界卫生组织结核病战略和技术咨询专家小组成员,全球抗击慢性呼吸疾病联盟副主席,全球慢病联盟董事会成员。《柳叶刀》新冠肺炎委员会成员。长期从事呼吸与危重症医学临床、教学与研究工作。主要研究领域包括呼吸病学、公共卫生和卫生政策研究等。在New Engl J Med、Lancet等国际权威期刊发表论文260余篇。
国家自然科学基金重大项目:慢阻肺早期疾病演进相关机制和靶标发现(2021-2025)
国家自然科学基金国际(地区)合作与交流项目:基于中英大规模队列研究的吸烟、慢性阻塞性肺疾病易感基因筛查及精准化戒烟治疗研究(2018-2022)
代表性论文:
1. Wang MY, Zhang Z, Liu JF*, Song MY, Zhang TT, Chen YL, HU HY, Yang PR, Li BL, Song XM, Pang JL, Xing YJ, Cao ZJ, Guo WJ, Yang H, Wang J*, Yang JT* and Wang C. Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omits study with drug exploration. Signal Transduction Target Ther. 2022; 7: 157. (IF:18.19)
2. Song M, Wang J, Sun Y, Pang J, Li X, Liu Y, Zhou Y, Yang P, Fan T, Li Z, Qi X, Li B, Zhang X*, Wang J*, Wang C*. Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis. Acta Pharm Sin B. 2022 Mar; 12(3): 1213–1224. (IF: 11.41)
3. Pang JL, Qi XM, Luo Y, Li XN, Shu T, Li BC, Song MY, Liu Y, Wei D, Wang J*, Chen Jingyu*, Wang C. Multi-omics study of silicosis reveals the potential therapeutic targets PGD2 and TXA2. Theranostics., 2021; 11(5): 2381-2394. (IF:11.56)
4. He Z, Ren L, Yang J, Guo L, Feng L, Ma C, Wang X, Leng Z, Tong X, Zhou W, Wang G, Zhang T, Guo Y, Wu C, Wang Q, Liu M, Wang C, Jia M, Hu X, Wang Y, Zhang X, Hu R, Zhong J, Yang J, Dai J, Chen L, Zhou X, Wang J*, Yang W*, Wang C*. Seroprevalence and humoral immune durability of anti-SARS-CoV-2 antibodies in Wuhan, China: a longitudinal, population-level, cross-sectional study. Lancet. 2021 Mar 20;397(10279):1075-1084. (IF:79.32)
5. Wang C*, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020 Feb 15;395(10223):470-473. (IF:79.32)
6. Chen S, Zhang Z, Yang J, Wang J, Zhai X, Bärnighausen T, Wang C*. Fangcang shelter hospitals: a novel concept for responding to public health emergencies. Lancet. 2020 Apr 18;395(10232):1305-1314. (IF:79.32)
7. Wang, Y., Zhang, D., Du, G., Du, R., Zhao, J., Jin, Y., Fu, S., Gao, L., Cheng, Z., Lu, Q., Hu, Y., Luo, G., Wang, K., Lu, Y., Li, H., Wang, S., Ruan, S., Yang, C., Mei, C., Wang, Y., Ding, D., Wu, F., Tang, X., Ye, X., Ye, Y., Liu, B., Yang, J., Yin, W., Wang, A., Fan, G., Zhou, F., Liu, Z., Gu, X., Xu, J., Shang, L., Zhang, Y., Cao, L., Guo, T., Wan, Y., Qin, H., Jiang, Y., Jaki, T., Hayden, F. G., Horby, P. W., Cao, B. & Wang, C. (2020) Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial, Lancet. 395, 1569-1578. (IF:79.32)
8. Chen, S., Yang, J., Yang, W., Wang, C. & Barnighausen, T. (2020) COVID-19 control in China during mass population movements at New Year, Lancet. 395, 764-766. (IF:79.32)
9. Wang, C., Chen, S., Zhu, J. & Li, W. (2019) China's new 4 + 4 medical education programme, Lancet. 394, 1121-1123. (IF:79.32)
10. Huang, K., Yang, T., Xu, J., Yang, L., Zhao, J., Zhang, X., Bai, C., Kang, J., Ran, P., Shen, H., Wen, F., Chen, Y., Sun, T., Shan, G., Lin, Y., Xu, G., Wu, S., Wang, C., Wang, R., Shi, Z., Xu, Y., Ye, X., Song, Y., Wang, Q., Zhou, Y., Li, W., Ding, L., Wan, C., Yao, W., Guo, Y., Xiao, F., Lu, Y., Peng, X., Zhang, B., Xiao, D., Wang, Z., Chen, Z., Bu, X., Zhang, H., Zhang, X., An, L., Zhang, S., Zhu, J., Cao, Z., Zhan, Q., Yang, Y., Liang, L., Tong, X., Dai, H., Cao, B., Wu, T., Chung, K. F., He, J., Wang, C. & China Pulmonary Health Study, G. (2019) Prevalence, risk factors, and management of asthma in China: a national cross-sectional study, Lancet. 394, 407-418. (IF:79.32)
11. Xiao, D. & Wang, C. (2019) Rising smoking epidemic among adolescents in China, The Lancet Respiratory medicine. 7, 3-5. (IF:30.70)
12. Wang, C., Xu, J., Yang, L., Xu, Y., Zhang, X., Bai, C., Kang, J., Ran, P., Shen, H., Wen, F., Huang, K., Yao, W., Sun, T., Shan, G., Yang, T., Lin, Y., Wu, S., Zhu, J., Wang, R., Shi, Z., Zhao, J., Ye, X., Song, Y., Wang, Q., Zhou, Y., Ding, L., Yang, T., Chen, Y., Guo, Y., Xiao, F., Lu, Y., Peng, X., Zhang, B., Xiao, D., Chen, C. S., Wang, Z., Zhang, H., Bu, X., Zhang, X., An, L., Zhang, S., Cao, Z., Zhan, Q., Yang, Y., Cao, B., Dai, H., Liang, L., He, J. & China Pulmonary Health Study, G. (2018) Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study, Lancet. 391, 1706-1717. (IF:79.32)
13. Wang, C. & Liu, Q. (2013) A turning point for clinical research in China?, Lancet. 382, 835-6. (IF:79.32)
代表性著作:
《内科学(第3版)》(供8年制及7年制临床医学专业教材) 主编(2015)
《内科学(第8版)》(本科生国家规划教材) 副主编(2014)
《呼吸与危重症医学》 主编(2011,2012,2013,2014,2015,2016)
《肺循环病学》主编(2007)
《肺栓塞》主编(2003)